Hemophilia is a genetic blood disorder caused by a deficiency of blood clotting factors. Hemophilia A occurs if there are abnormalities in the gene that causes a lack of clotting factor VIII (FVIII). Hemophilia B lack of clotting factor IX (FIX). Hemophilia A and B cannot be distinguished because it has a similar clinical appearance and a similar pattern of gene inheritance.
Hemophilia is a genetic disease of the oldest ever recorded. Inherited bleeding disorder that occurs in a male was recorded in file Talmud in the Second Century. Modern history of hemophilia began in 1803 by John Otto was there a child who suffered from hemophilia.
Proof disability in process of blood clotting in hemophilia conducted by Wright in 1893. However, factor VIII (FVIII) have not been identified until 1937 when Patek and Taylor managed to isolate from the blood clotting factor, which was called anti hemophilia factor (AHF).
In the early 1960s, cryoprecipitate was the first time there's concentrate for the treatment of hemophilia. In the 1970s, lyophilized intermediate-purity concentrates concentrate or pure medium liofil first created from a collection of donor blood. Since then hemophilia therapy dramatically successful in increasing the life expectancy of sufferers and can facilitate them to surgery and treatment at home.
Hemophilia suffered most in only in men. Women will truly have hemophilia if his father was a carrier of hemophilia and the mother is a trait (carrier). Hemophilia A or B is a disease that is rarely found. Hemophilia A occurs 1 among 10,000 people. Hemophilia B is less common, is 1 of 50,000 people.
Source from: Wikipedia
The most common bleeding disorder in women and girls is von Willebrand disease (VWD). It affects up to 1% of the U.S. population. VWD is an inherited bleeding disorder. It is caused by a defect in or deficiency of von Willebrand factor, a protein the blood needs for clotting.
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